Matthew Truszkowski, a socially inept eighteen-year-old from Illinois, is presented with the opportunity of a lifetime. He is promised extreme wealth, fame, and an incredibly bright future in exchange for one service: He, along with forty other "lucky", specially selected high school students from across the United States, must participate in a medical research experiment for a total of eight months. However, the details of the experiment remain oddly unspecific, and as it progresses, Matt begins to suspect that there is something very wrong about the whole thing... and that he has to figure it out before it is too late.