世界非常殘酷，美味可口的食物很多時候都是高脂高卡路里。966Please respect copyright.ＰＥＮＡＮＡJtsS55RypE
966Please respect copyright.ＰＥＮＡＮＡu04emzvvQ7
966Please respect copyright.ＰＥＮＡＮＡ5PYyIAoBRG
如果餐單的卡路里長期是以脂肪為主導的話，又是否會更容易產生癌症呢?966Please respect copyright.ＰＥＮＡＮＡRXYphNoxpy
966Please respect copyright.ＰＥＮＡＮＡiO8PBb2Dbi
（圖2）有科學家對此進行研究（Ref1)，餵食老鼠為期7日脂肪佔總卡路里約60%的餐單，然後再透過血管移植人類的口腔癌細胞，其後密切跟進腫瘤的狀況。966Please respect copyright.ＰＥＮＡＮＡ4wfzL1bxwA
966Please respect copyright.ＰＥＮＡＮＡigfviemCEu
966Please respect copyright.ＰＥＮＡＮＡ00no1tpJzK
如何跟進? 就是用上集所介紹的螢光技術。966Please respect copyright.ＰＥＮＡＮＡ5r4AB6sthW
966Please respect copyright.ＰＥＮＡＮＡiEE2vPqU6o
詳情可見：三十秒科學–透視癌細胞966Please respect copyright.ＰＥＮＡＮＡ1nNyR4lDEC
- 分享自 LIHKG 討論區966Please respect copyright.ＰＥＮＡＮＡI76ULxbLZw
https://lih.kg/2408323966Please respect copyright.ＰＥＮＡＮＡzefg5flNsF
966Please respect copyright.ＰＥＮＡＮＡkMNLZdY9EF
966Please respect copyright.ＰＥＮＡＮＡEnxRjfC8cX
（圖3）從圖中可以看得見，進食脂肪主導餐單的老鼠，原生腫瘤的體積不但更為巨大，而且亦有更高機率出現癌細胞轉移的情況。966Please respect copyright.ＰＥＮＡＮＡAOvmDct87T
966Please respect copyright.ＰＥＮＡＮＡmdNUycVTqc
966Please respect copyright.ＰＥＮＡＮＡ3nbHfTfGvc
CD36是輔助細胞吸取脂肪酸的蛋白質，當癌細胞的CD36被除去的時候，莫論餐單是否由脂肪主導，原生腫瘤的體積均沒有顯著大變化，而且亦沒有出現癌細胞轉移的情況。966Please respect copyright.ＰＥＮＡＮＡ5ayoZ9MlTR
966Please respect copyright.ＰＥＮＡＮＡ2Fq2tyqemS
（圖4）當細胞遇上棕櫚酸約兩日後，細胞的CD36蛋白質數量亦會因而上升 。966Please respect copyright.ＰＥＮＡＮＡlqPtbXBZmv
966Please respect copyright.ＰＥＮＡＮＡcL6qB7naJf
966Please respect copyright.ＰＥＮＡＮＡ15LMFHzY5a
從右圖中可以清晰見得到，經過棕櫚酸「調教」過的癌細胞，移植到老鼠後會出現非常明顯的癌細胞轉移過程。966Please respect copyright.ＰＥＮＡＮＡVlF0Unhj0B
而當癌細胞的CD36蛋白質被移除後，癌細胞轉移過程亦再沒有發生。966Please respect copyright.ＰＥＮＡＮＡtGrevNzjjW
966Please respect copyright.ＰＥＮＡＮＡleJrWQj8R9
現時有不少藥物嘗試針對CD36來醫治癌細胞或阻止其進行轉移的程序，但不少藥物均在第二期臨床研究裡頭因為出現副作用或效率未如預期被迫中斷。966Please respect copyright.ＰＥＮＡＮＡ2MHQh5fDhB
966Please respect copyright.ＰＥＮＡＮＡe02QjSb6BP
或許需要更多研究理解CD36在細胞的作用或機制，才能設計出輕微副作用的治癌藥物。966Please respect copyright.ＰＥＮＡＮＡwvv1l4orNN
966Please respect copyright.ＰＥＮＡＮＡMzmnVeSdj8
966Please respect copyright.ＰＥＮＡＮＡbHBW9nPIPs
如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。966Please respect copyright.ＰＥＮＡＮＡw2ZEg1XVtD
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Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc966Please respect copyright.ＰＥＮＡＮＡ0OwZpi202X
966Please respect copyright.ＰＥＮＡＮＡNtyfAReH7P
同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。966Please respect copyright.ＰＥＮＡＮＡCKOPMtABG1
966Please respect copyright.ＰＥＮＡＮＡKTbvtH2peL
Link:966Please respect copyright.ＰＥＮＡＮＡXpFJoY6BxC
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio966Please respect copyright.ＰＥＮＡＮＡdWbNHkJm2X
966Please respect copyright.ＰＥＮＡＮＡ6l813S6YpD
966Please respect copyright.ＰＥＮＡＮＡExL5zGIaJl
除非Facebook及IG重開侵侵的account，否則我的IG將不會再作更新，只會寄居本土LIHKG及Penana。966Please respect copyright.ＰＥＮＡＮＡjlWaAmTEBb
966Please respect copyright.ＰＥＮＡＮＡtA6380lyoA
Ref1:https://pubmed.ncbi.nlm.nih.gov/27974793/966Please respect copyright.ＰＥＮＡＮＡB0vU7ILqPF
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