世界非常殘酷，美味可口的食物很多時候都是高脂高卡路里。988Please respect copyright.ＰＥＮＡＮＡl8KHierArz
988Please respect copyright.ＰＥＮＡＮＡtM4pSN8vx4
988Please respect copyright.ＰＥＮＡＮＡi6cjKy4GVO
如果餐單的卡路里長期是以脂肪為主導的話，又是否會更容易產生癌症呢?988Please respect copyright.ＰＥＮＡＮＡBa2tfAcK16
988Please respect copyright.ＰＥＮＡＮＡ5HSSNycYGi
（圖2）有科學家對此進行研究（Ref1)，餵食老鼠為期7日脂肪佔總卡路里約60%的餐單，然後再透過血管移植人類的口腔癌細胞，其後密切跟進腫瘤的狀況。988Please respect copyright.ＰＥＮＡＮＡ8SYeGAwsqs
988Please respect copyright.ＰＥＮＡＮＡC3elP80yVD
988Please respect copyright.ＰＥＮＡＮＡpeXxlJIsHH
如何跟進? 就是用上集所介紹的螢光技術。988Please respect copyright.ＰＥＮＡＮＡoXhWDiBxA0
988Please respect copyright.ＰＥＮＡＮＡMFSWXbhUsC
詳情可見：三十秒科學–透視癌細胞988Please respect copyright.ＰＥＮＡＮＡOcCx8UKNos
- 分享自 LIHKG 討論區988Please respect copyright.ＰＥＮＡＮＡNDeMQHncEx
https://lih.kg/2408323988Please respect copyright.ＰＥＮＡＮＡfKT2H6GFpa
988Please respect copyright.ＰＥＮＡＮＡhFtogveLMA
988Please respect copyright.ＰＥＮＡＮＡ5PTPjOnRCa
（圖3）從圖中可以看得見，進食脂肪主導餐單的老鼠，原生腫瘤的體積不但更為巨大，而且亦有更高機率出現癌細胞轉移的情況。988Please respect copyright.ＰＥＮＡＮＡNsOZKL4xTI
988Please respect copyright.ＰＥＮＡＮＡ0Qx02VMEy5
988Please respect copyright.ＰＥＮＡＮＡur3mx0YhQ3
CD36是輔助細胞吸取脂肪酸的蛋白質，當癌細胞的CD36被除去的時候，莫論餐單是否由脂肪主導，原生腫瘤的體積均沒有顯著大變化，而且亦沒有出現癌細胞轉移的情況。988Please respect copyright.ＰＥＮＡＮＡBQzgASr6FH
988Please respect copyright.ＰＥＮＡＮＡMYxpZLFXeF
（圖4）當細胞遇上棕櫚酸約兩日後，細胞的CD36蛋白質數量亦會因而上升 。988Please respect copyright.ＰＥＮＡＮＡoNDspMXVJ7
988Please respect copyright.ＰＥＮＡＮＡsFQmyvY8na
988Please respect copyright.ＰＥＮＡＮＡxiDlE8hQqM
從右圖中可以清晰見得到，經過棕櫚酸「調教」過的癌細胞，移植到老鼠後會出現非常明顯的癌細胞轉移過程。988Please respect copyright.ＰＥＮＡＮＡ3l597SV6IP
而當癌細胞的CD36蛋白質被移除後，癌細胞轉移過程亦再沒有發生。988Please respect copyright.ＰＥＮＡＮＡqqWW8DS5tJ
988Please respect copyright.ＰＥＮＡＮＡQ8lMY3gnaK
現時有不少藥物嘗試針對CD36來醫治癌細胞或阻止其進行轉移的程序，但不少藥物均在第二期臨床研究裡頭因為出現副作用或效率未如預期被迫中斷。988Please respect copyright.ＰＥＮＡＮＡ2jIopHaLOP
988Please respect copyright.ＰＥＮＡＮＡEo1RSviFVI
或許需要更多研究理解CD36在細胞的作用或機制，才能設計出輕微副作用的治癌藥物。988Please respect copyright.ＰＥＮＡＮＡwfEhhSA0Dh
988Please respect copyright.ＰＥＮＡＮＡRiwUBMlFvN
988Please respect copyright.ＰＥＮＡＮＡOfOchBZ6F9
如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。988Please respect copyright.ＰＥＮＡＮＡyLxYigsUbr
988Please respect copyright.ＰＥＮＡＮＡUi5JEOWyb4
Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc988Please respect copyright.ＰＥＮＡＮＡeu87RbF5pj
988Please respect copyright.ＰＥＮＡＮＡxyKyqi4CZP
同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。988Please respect copyright.ＰＥＮＡＮＡmagRrX5TC7
988Please respect copyright.ＰＥＮＡＮＡWCIiVdPTC1
Link:988Please respect copyright.ＰＥＮＡＮＡkrkw1HgglW
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio988Please respect copyright.ＰＥＮＡＮＡ3QdkYTYHWk
988Please respect copyright.ＰＥＮＡＮＡ9NcvpTZOTJ
988Please respect copyright.ＰＥＮＡＮＡ6F9cToEJh7
除非Facebook及IG重開侵侵的account，否則我的IG將不會再作更新，只會寄居本土LIHKG及Penana。988Please respect copyright.ＰＥＮＡＮＡ3jUfi9SNtc
988Please respect copyright.ＰＥＮＡＮＡXC4OVgxjvj
Ref1:https://pubmed.ncbi.nlm.nih.gov/27974793/988Please respect copyright.ＰＥＮＡＮＡ3VqHpalkYb
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