我們身體的各部份均是由細胞組成，眼睛晶片也自當然不例外。764Please respect copyright.ＰＥＮＡＮＡ1ogs52Hzaj
但細胞裡頭有著各式各樣的細胞器官，例如負責製造能源的粒線體(mitochondria)、收藏DNA的細胞核(nucleus)等，它們顯然並不是透明的。764Please respect copyright.ＰＥＮＡＮＡJlJVIDGiyu
764Please respect copyright.ＰＥＮＡＮＡ5HXbZJwgAW
究竟身體有甚麼方法可以製造透明且能讓光線通過的眼鏡晶片呢?764Please respect copyright.ＰＥＮＡＮＡW3IBM4S9G3
764Please respect copyright.ＰＥＮＡＮＡorw80Xj6Wd
764Please respect copyright.ＰＥＮＡＮＡCi13HPfcU9
764Please respect copyright.ＰＥＮＡＮＡcNpQRnqSVe
(圖2)答案很簡單，就是把那些細胞器官通通摧毀。764Please respect copyright.ＰＥＮＡＮＡFTOhl2g2Bv
764Please respect copyright.ＰＥＮＡＮＡhUTga6t5EN
764Please respect copyright.ＰＥＮＡＮＡKYMu8rVm8t
從圖中可見，晶片的外圍有著表皮細胞(Epithelial cells)以及纖維細胞(Fibre cells)，唯獨是中間區域的細胞，它們的細胞器官均接近得消失得一乾二淨。764Please respect copyright.ＰＥＮＡＮＡLiLqcty6BE
764Please respect copyright.ＰＥＮＡＮＡeduinhv2yC
764Please respect copyright.ＰＥＮＡＮＡ0kjnhq8X1W
(圖3)有科學家利用班馬魚作動物模型，並將兩款細胞器官分別染成綠色及紅色。764Please respect copyright.ＰＥＮＡＮＡGi5bS8PE6h
764Please respect copyright.ＰＥＮＡＮＡcZKbBhGq9z
764Please respect copyright.ＰＥＮＡＮＡTNb6ctoQTj
從圖中可見，直至班馬魚受精後約59小時左右，綠色及紅色均分別清晰可見及有著其獨特的分佈，表示兩款細胞器官非常健在。764Please respect copyright.ＰＥＮＡＮＡ8016lxdqCM
但在約60小時打後，紅色和綠色開始有著衰退的現象，亦即表示細胞器官開始逐漸被受摧毀。764Please respect copyright.ＰＥＮＡＮＡsPJ6OiuSoH
764Please respect copyright.ＰＥＮＡＮＡXW6xEuHrTA
764Please respect copyright.ＰＥＮＡＮＡBL8UB3s0Jk
(圖4)找出眼睛晶片的細胞器官被受摧毀的時段後，研究人員便著手進行一系列的實驗，764Please respect copyright.ＰＥＮＡＮＡD5zLZ4pGAM
並發現名為plaat的蛋白質負責在細胞器官的外膜進行破壞，因而引發細胞器官摧毀的過程。764Please respect copyright.ＰＥＮＡＮＡUrRwmT1gPw
764Please respect copyright.ＰＥＮＡＮＡhWFKfy3CsW
764Please respect copyright.ＰＥＮＡＮＡPGOLMx3ysC
圖中為班馬魚的眼睛晶片，可見因為缺乏plaat蛋白質的緣故，細胞器官沒能完整摧毀，其晶片亦變得相對上混濁及不透光，影像亦較為不清晰。764Please respect copyright.ＰＥＮＡＮＡXyMlPHVyqu
764Please respect copyright.ＰＥＮＡＮＡZna3xDRZ6y
764Please respect copyright.ＰＥＮＡＮＡ61e3ds46pk
(圖5)除班馬魚外，研究人員亦有利用老鼠進行實驗。764Please respect copyright.ＰＥＮＡＮＡpfWuRqvifa
764Please respect copyright.ＰＥＮＡＮＡHnpU2TY9XE
764Please respect copyright.ＰＥＮＡＮＡBL9rr2X42K
跟班馬魚一樣，缺乏plaat蛋白質的老鼠眼睛晶片變得混濁及不透光，並影響視線。764Please respect copyright.ＰＥＮＡＮＡZ4E2Do834k
764Please respect copyright.ＰＥＮＡＮＡA2GaJ9hXYQ
764Please respect copyright.ＰＥＮＡＮＡgRGbxAuC83
764Please respect copyright.ＰＥＮＡＮＡexmXa10pEl
764Please respect copyright.ＰＥＮＡＮＡEBysBk0DB4
764Please respect copyright.ＰＥＮＡＮＡvHV13wqKHp
如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。764Please respect copyright.ＰＥＮＡＮＡC2aPctL46w
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Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc764Please respect copyright.ＰＥＮＡＮＡjDGzYUekBc
764Please respect copyright.ＰＥＮＡＮＡt1DFCCCSSG
同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。764Please respect copyright.ＰＥＮＡＮＡJG3Uel7CpW
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Link:764Please respect copyright.ＰＥＮＡＮＡzurGa0HZVG
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio764Please respect copyright.ＰＥＮＡＮＡ6QMDwZcFW0
764Please respect copyright.ＰＥＮＡＮＡGqocTXP5Og
764Please respect copyright.ＰＥＮＡＮＡz4RyYnNlkc
除非Facebook及IG重開侵侵的account，否則我的IG將不會再作更新，只會寄居本土LIHKG及Penana。764Please respect copyright.ＰＥＮＡＮＡSVGJoK8Y0N
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Ref1:https://www.nature.com/articles/s41586-021-03439-w764Please respect copyright.ＰＥＮＡＮＡVbmDBwmrIN
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