我們身體的各部份均是由細胞組成，眼睛晶片也自當然不例外。830Please respect copyright.ＰＥＮＡＮＡkc9496ajGD
但細胞裡頭有著各式各樣的細胞器官，例如負責製造能源的粒線體(mitochondria)、收藏DNA的細胞核(nucleus)等，它們顯然並不是透明的。830Please respect copyright.ＰＥＮＡＮＡmipMmesZzq
830Please respect copyright.ＰＥＮＡＮＡ86cCk3QvMV
究竟身體有甚麼方法可以製造透明且能讓光線通過的眼鏡晶片呢?830Please respect copyright.ＰＥＮＡＮＡ3Q85c0sS88
830Please respect copyright.ＰＥＮＡＮＡeTKtU7nSjW
830Please respect copyright.ＰＥＮＡＮＡrhCli5gAWZ
830Please respect copyright.ＰＥＮＡＮＡLS7nQUkYWD
(圖2)答案很簡單，就是把那些細胞器官通通摧毀。830Please respect copyright.ＰＥＮＡＮＡ8klw6pUAyE
830Please respect copyright.ＰＥＮＡＮＡPO6qQ8hHth
830Please respect copyright.ＰＥＮＡＮＡtJ4vqDUFbZ
從圖中可見，晶片的外圍有著表皮細胞(Epithelial cells)以及纖維細胞(Fibre cells)，唯獨是中間區域的細胞，它們的細胞器官均接近得消失得一乾二淨。830Please respect copyright.ＰＥＮＡＮＡl7Gx3pp8Ih
830Please respect copyright.ＰＥＮＡＮＡ5hW7qhxFPI
830Please respect copyright.ＰＥＮＡＮＡrrxKzM5IV8
(圖3)有科學家利用班馬魚作動物模型，並將兩款細胞器官分別染成綠色及紅色。830Please respect copyright.ＰＥＮＡＮＡAjoozB2qaD
830Please respect copyright.ＰＥＮＡＮＡBLoYp8faZX
830Please respect copyright.ＰＥＮＡＮＡ9L7JyaZLV2
從圖中可見，直至班馬魚受精後約59小時左右，綠色及紅色均分別清晰可見及有著其獨特的分佈，表示兩款細胞器官非常健在。830Please respect copyright.ＰＥＮＡＮＡEdnjxTaPBZ
但在約60小時打後，紅色和綠色開始有著衰退的現象，亦即表示細胞器官開始逐漸被受摧毀。830Please respect copyright.ＰＥＮＡＮＡb1rutrSXEl
830Please respect copyright.ＰＥＮＡＮＡP0ehTlbWAU
830Please respect copyright.ＰＥＮＡＮＡ9ymRpALMyG
(圖4)找出眼睛晶片的細胞器官被受摧毀的時段後，研究人員便著手進行一系列的實驗，830Please respect copyright.ＰＥＮＡＮＡYqGx7VEETV
並發現名為plaat的蛋白質負責在細胞器官的外膜進行破壞，因而引發細胞器官摧毀的過程。830Please respect copyright.ＰＥＮＡＮＡo0EZvkxtee
830Please respect copyright.ＰＥＮＡＮＡ6htmrHCOKP
830Please respect copyright.ＰＥＮＡＮＡlelbTLKpHX
圖中為班馬魚的眼睛晶片，可見因為缺乏plaat蛋白質的緣故，細胞器官沒能完整摧毀，其晶片亦變得相對上混濁及不透光，影像亦較為不清晰。830Please respect copyright.ＰＥＮＡＮＡivZAKaKiaE
830Please respect copyright.ＰＥＮＡＮＡLQW0p3K2lb
830Please respect copyright.ＰＥＮＡＮＡSYlYtgDLpC
(圖5)除班馬魚外，研究人員亦有利用老鼠進行實驗。830Please respect copyright.ＰＥＮＡＮＡ1ThebnRPkr
830Please respect copyright.ＰＥＮＡＮＡo73E4EarDB
830Please respect copyright.ＰＥＮＡＮＡVVXQB8OdlQ
跟班馬魚一樣，缺乏plaat蛋白質的老鼠眼睛晶片變得混濁及不透光，並影響視線。830Please respect copyright.ＰＥＮＡＮＡSTyMPQso1J
830Please respect copyright.ＰＥＮＡＮＡgis6tv176N
830Please respect copyright.ＰＥＮＡＮＡa0ZHzlMSLI
830Please respect copyright.ＰＥＮＡＮＡMuFSkMa1Ib
830Please respect copyright.ＰＥＮＡＮＡUyvy1dRlxM
830Please respect copyright.ＰＥＮＡＮＡ6XKDd8c3eQ
如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。830Please respect copyright.ＰＥＮＡＮＡuB0uG4dXKr
830Please respect copyright.ＰＥＮＡＮＡ2TaNecEWwT
Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc830Please respect copyright.ＰＥＮＡＮＡsdB5trsp5j
830Please respect copyright.ＰＥＮＡＮＡd7nhcUcY2n
同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。830Please respect copyright.ＰＥＮＡＮＡzC779bMD4K
830Please respect copyright.ＰＥＮＡＮＡHkHs5tGPBR
Link:830Please respect copyright.ＰＥＮＡＮＡmPTXz1cPO2
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio830Please respect copyright.ＰＥＮＡＮＡskttb619wP
830Please respect copyright.ＰＥＮＡＮＡkxHfXiSl7g
830Please respect copyright.ＰＥＮＡＮＡCteSE4MQIZ
除非Facebook及IG重開侵侵的account，否則我的IG將不會再作更新，只會寄居本土LIHKG及Penana。830Please respect copyright.ＰＥＮＡＮＡBOEAP0EaBN
830Please respect copyright.ＰＥＮＡＮＡi9HkT6IvUt
Ref1:https://www.nature.com/articles/s41586-021-03439-w830Please respect copyright.ＰＥＮＡＮＡbFR9oewmKF
Penana
search
登入arrow_drop_down
註冊arrow_drop_down
