過度開採環境，最終受害的只會是人類自己。879Please respect copyright.ＰＥＮＡＮＡLe2Wv2mkGn
879Please respect copyright.ＰＥＮＡＮＡpcEmjnZNkQ
（圖1）19世紀，日本三井金屬礦業的神岡礦山過度開採，排出的重金屬累積在泥土裡頭，導致河旁的稻田穀物受到鎘(Cadmium)重金屬污染。879Please respect copyright.ＰＥＮＡＮＡyCLkSYjbzW
879Please respect copyright.ＰＥＮＡＮＡBpGqxQCOJM
879Please respect copyright.ＰＥＮＡＮＡ4DjYEwooDE
不知情的居民長期服用鎘污染的稻米，骨骼逐漸變得鬆脆，腎臟亦受到嚴重傷害。879Please respect copyright.ＰＥＮＡＮＡYiBDnJWL3d
最終日本醫生成功證實得到病因來自攝取過量的重金屬鎘，並把患者經常呻痛的病徵命名為痛痛病(Itai-itai disease)。879Please respect copyright.ＰＥＮＡＮＡI9U77LFleR
879Please respect copyright.ＰＥＮＡＮＡKderv4cHO6
而稻米的鎘含度自此受到重視，世衛WHO更將大麥的鎘上限設為0.1mg kg−1，亦即是每一公斤大麥只可有一微克鎘。879Please respect copyright.ＰＥＮＡＮＡwoOXCQhSes
879Please respect copyright.ＰＥＮＡＮＡKECQ6nScCc
879Please respect copyright.ＰＥＮＡＮＡw99sgRKZ9j
（圖2）一直以來，科學家已找出不少穀物吸取或代謝重金屬的基因，把穀物改造，盡量減低重金屬累積在穀物的程度。879Please respect copyright.ＰＥＮＡＮＡ6uVtpih8Ey
879Please respect copyright.ＰＥＮＡＮＡfcS5Ziiryf
879Please respect copyright.ＰＥＮＡＮＡGrAWeBX8sm
近日有科學家比較世界100款大麥的鎘數量(Ref1)，發現日本一款Haruna Nijo大麥的鎘含量最高(0.04mg kg−1），而阿富汗BCS318大麥款式則為最低(0.01mg kg−1）。879Please respect copyright.ＰＥＮＡＮＡfm9bpY09Ao
879Please respect copyright.ＰＥＮＡＮＡ40pTeCF7z1
（圖3）一輪比較過後，科學家證實阿富汗大麥的HvHMA3蛋白質數量比較多，為大麥減少吸收泥土鎘金屬的主因。879Please respect copyright.ＰＥＮＡＮＡxjsDA0g9pv
879Please respect copyright.ＰＥＮＡＮＡ538QbV6dmH
879Please respect copyright.ＰＥＮＡＮＡEQ8aVn7tVb
最後證實，歸根原因是一段特定的基因安插在HvHMA3蛋白質基因的前頭，催促HvHMA3蛋白質的產生。879Please respect copyright.ＰＥＮＡＮＡPjiMO70hH9
879Please respect copyright.ＰＥＮＡＮＡHLqDFS0dZN
科學家後來再找尋另外334款大麥，發覺有54種同樣被安插在同樣位置，而那54款品種又的確是含有較少的鎘金屬數量。879Please respect copyright.ＰＥＮＡＮＡ5TNxGozLeV
879Please respect copyright.ＰＥＮＡＮＡpMlCziMXYl
879Please respect copyright.ＰＥＮＡＮＡWopDUfLwdY
最後，科學家把那段基因插在日本Haruna Nijo大麥的適當位置上，同樣亦能將鎘金屬數量減至與阿富汗品種相同，而產量及其他各種礦物質的含量並沒有任何的大改變。879Please respect copyright.ＰＥＮＡＮＡp5EKY8UMek
879Please respect copyright.ＰＥＮＡＮＡqkLH8pI1Wo
此基因的排序及位置已公開在資料庫上，好讓各種基因學家或相關人士可作參考盡量減低日後穀物的鎘金屬數量。879Please respect copyright.ＰＥＮＡＮＡCkgdzn6JO9
879Please respect copyright.ＰＥＮＡＮＡq3TvzgBo1b
879Please respect copyright.ＰＥＮＡＮＡkwdFDVMXoK
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如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。879Please respect copyright.ＰＥＮＡＮＡKLexoOe6Hx
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Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc879Please respect copyright.ＰＥＮＡＮＡjUmpkFMUr7
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同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。879Please respect copyright.ＰＥＮＡＮＡurfVhhdsPN
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Link:879Please respect copyright.ＰＥＮＡＮＡGzEETtzl8B
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio879Please respect copyright.ＰＥＮＡＮＡdMsoLRRN4y
879Please respect copyright.ＰＥＮＡＮＡRuyN9uBn0K
879Please respect copyright.ＰＥＮＡＮＡYFU1HsUFXM
有興趣接收科普資訊的話，歡迎follow IG: potatopigtongue。879Please respect copyright.ＰＥＮＡＮＡBRKyZS9cbS
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Ref1:https://www.nature.com/articles/s43016-020-0130-x879Please respect copyright.ＰＥＮＡＮＡKnPmNZBHdh
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