我們身體的各部份均是由細胞組成，眼睛晶片也自當然不例外。781Please respect copyright.ＰＥＮＡＮＡhRRGi9rmNg
但細胞裡頭有著各式各樣的細胞器官，例如負責製造能源的粒線體(mitochondria)、收藏DNA的細胞核(nucleus)等，它們顯然並不是透明的。781Please respect copyright.ＰＥＮＡＮＡSxeG3ATivK
781Please respect copyright.ＰＥＮＡＮＡBZaCXPHyDs
究竟身體有甚麼方法可以製造透明且能讓光線通過的眼鏡晶片呢?781Please respect copyright.ＰＥＮＡＮＡwAbX7zAorv
781Please respect copyright.ＰＥＮＡＮＡyEivi1QCZm
781Please respect copyright.ＰＥＮＡＮＡGr0Q6opLsb
781Please respect copyright.ＰＥＮＡＮＡtJHBo1Ykiw
(圖2)答案很簡單，就是把那些細胞器官通通摧毀。781Please respect copyright.ＰＥＮＡＮＡOouS5nYIC0
781Please respect copyright.ＰＥＮＡＮＡtnArrmevhc
781Please respect copyright.ＰＥＮＡＮＡgS7CNCkuSp
從圖中可見，晶片的外圍有著表皮細胞(Epithelial cells)以及纖維細胞(Fibre cells)，唯獨是中間區域的細胞，它們的細胞器官均接近得消失得一乾二淨。781Please respect copyright.ＰＥＮＡＮＡysvkuRrEeR
781Please respect copyright.ＰＥＮＡＮＡXKBwA4yWhm
781Please respect copyright.ＰＥＮＡＮＡUaVJK9ffR7
(圖3)有科學家利用班馬魚作動物模型，並將兩款細胞器官分別染成綠色及紅色。781Please respect copyright.ＰＥＮＡＮＡx3rztcxxKn
781Please respect copyright.ＰＥＮＡＮＡIj6zf8vULG
781Please respect copyright.ＰＥＮＡＮＡocEhVrIK0q
從圖中可見，直至班馬魚受精後約59小時左右，綠色及紅色均分別清晰可見及有著其獨特的分佈，表示兩款細胞器官非常健在。781Please respect copyright.ＰＥＮＡＮＡk8FYPtBXVF
但在約60小時打後，紅色和綠色開始有著衰退的現象，亦即表示細胞器官開始逐漸被受摧毀。781Please respect copyright.ＰＥＮＡＮＡ18oiSLkXhS
781Please respect copyright.ＰＥＮＡＮＡEK301ENzqZ
781Please respect copyright.ＰＥＮＡＮＡruM7ab3Knb
(圖4)找出眼睛晶片的細胞器官被受摧毀的時段後，研究人員便著手進行一系列的實驗，781Please respect copyright.ＰＥＮＡＮＡamucng7vcB
並發現名為plaat的蛋白質負責在細胞器官的外膜進行破壞，因而引發細胞器官摧毀的過程。781Please respect copyright.ＰＥＮＡＮＡ22OjI8jP1S
781Please respect copyright.ＰＥＮＡＮＡWloZlodhV1
781Please respect copyright.ＰＥＮＡＮＡyYcwKlLkAx
圖中為班馬魚的眼睛晶片，可見因為缺乏plaat蛋白質的緣故，細胞器官沒能完整摧毀，其晶片亦變得相對上混濁及不透光，影像亦較為不清晰。781Please respect copyright.ＰＥＮＡＮＡbQNDbPzisY
781Please respect copyright.ＰＥＮＡＮＡH8lD5PWxka
781Please respect copyright.ＰＥＮＡＮＡbPAGHGqdUd
(圖5)除班馬魚外，研究人員亦有利用老鼠進行實驗。781Please respect copyright.ＰＥＮＡＮＡDP4Qv1HO8A
781Please respect copyright.ＰＥＮＡＮＡH8Hn7Xdupj
781Please respect copyright.ＰＥＮＡＮＡvyEopVZn72
跟班馬魚一樣，缺乏plaat蛋白質的老鼠眼睛晶片變得混濁及不透光，並影響視線。781Please respect copyright.ＰＥＮＡＮＡ5h9PGDKVBl
781Please respect copyright.ＰＥＮＡＮＡlTy46W8Rua
781Please respect copyright.ＰＥＮＡＮＡW86lv35M6U
781Please respect copyright.ＰＥＮＡＮＡhdZAQQ3y3L
781Please respect copyright.ＰＥＮＡＮＡQo7lquYGEC
781Please respect copyright.ＰＥＮＡＮＡq5nvILKDPE
如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。781Please respect copyright.ＰＥＮＡＮＡmL7shXOi2P
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Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc781Please respect copyright.ＰＥＮＡＮＡ2Mzta0fK5I
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同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。781Please respect copyright.ＰＥＮＡＮＡk6qhB8iITG
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Link:781Please respect copyright.ＰＥＮＡＮＡhQcVT6Fid7
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio781Please respect copyright.ＰＥＮＡＮＡ0BJjMBLMz8
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除非Facebook及IG重開侵侵的account，否則我的IG將不會再作更新，只會寄居本土LIHKG及Penana。781Please respect copyright.ＰＥＮＡＮＡyS3cpYJT6X
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Ref1:https://www.nature.com/articles/s41586-021-03439-w781Please respect copyright.ＰＥＮＡＮＡVxZPnFYW7I
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