季節性流感造成全球每年約290,000-650,000人的死亡。886Please respect copyright.ＰＥＮＡＮＡ8OLdpFx3wr
886Please respect copyright.ＰＥＮＡＮＡWZsWFleQeR
886Please respect copyright.ＰＥＮＡＮＡNK5bDSvZg9
流感病毒接近每年均會出現變種，基於現時並無統一疫苗對抗各品種，所以很多時候在翌年便要轉換對應的疫苗。886Please respect copyright.ＰＥＮＡＮＡehR7Wvh7pF
886Please respect copyright.ＰＥＮＡＮＡAd9yDMmhfZ
(圖2)流感病毒外部、名為HA的部份，將主宰病毒能否進入人體細胞裡頭。886Please respect copyright.ＰＥＮＡＮＡzmlbA6PHz9
886Please respect copyright.ＰＥＮＡＮＡEwcymEvSLP
886Please respect copyright.ＰＥＮＡＮＡ0n53DuqDCh
流感病毒的變異較常出現在頭部位置(Head)，而現時疫苗的設計亦主要針對HA的頭部位置。886Please respect copyright.ＰＥＮＡＮＡ2lX00Qxh15
886Please respect copyright.ＰＥＮＡＮＡPbmrdiR9Pq
其目標是希望人們注射疫苗後，體內會產生對應HA頭部位置的抗體，阻止病毒進入人體細胞繼而作惡。886Please respect copyright.ＰＥＮＡＮＡs7c3l8wCQa
886Please respect copyright.ＰＥＮＡＮＡSzNJObSfzp
(圖3)另一方面來想，流感病毒變種就如不同顏色的花朵一樣。886Please respect copyright.ＰＥＮＡＮＡKtfkRqzH9B
886Please respect copyright.ＰＥＮＡＮＡcUIYExlXKx
886Please respect copyright.ＰＥＮＡＮＡ4nWZSYCFNl
雖然花朵各有不同，但莖部位置則大同小異。886Please respect copyright.ＰＥＮＡＮＡdGJrQsQFZj
886Please respect copyright.ＰＥＮＡＮＡnbsw91ydaM
(圖4)基於Stalk位置(花朵莖部位置)的變異成數較細，現時科學家正研發針對Stalk位置的疫苗(Ref1)，希望可以透過一款疫苗對抗多款流感變種。886Please respect copyright.ＰＥＮＡＮＡS2IoOxBk4e
886Please respect copyright.ＰＥＮＡＮＡOCeMkrnS56
886Please respect copyright.ＰＥＮＡＮＡhuTaaN8AYG
這類型的疫苗現時已進入Phase1狀態，人體試驗找來了51名人士，注射疫苗後體內亦得出相應的大量抗體。886Please respect copyright.ＰＥＮＡＮＡNxySIbO6VJ
886Please respect copyright.ＰＥＮＡＮＡenUVddYwQi
而日後所進行的人體試驗，將會能夠獲取資料測量疫苗能否達到預防流感之效。886Please respect copyright.ＰＥＮＡＮＡm9iS0s6m7X
886Please respect copyright.ＰＥＮＡＮＡryNRZWTQyT
若安全性、效率等等均達到合理水平的話，將來不但之可以不用經常轉換疫苗款式，亦能大大減低疫苗與當下流感款式不吻合的機會，皆大歡喜。886Please respect copyright.ＰＥＮＡＮＡACtKRTIoyX
886Please respect copyright.ＰＥＮＡＮＡqDJJoTbos4
如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。886Please respect copyright.ＰＥＮＡＮＡpV6AcLLP6d
886Please respect copyright.ＰＥＮＡＮＡCitEnhCsHU
Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc886Please respect copyright.ＰＥＮＡＮＡkjbYVJU9vO
886Please respect copyright.ＰＥＮＡＮＡ56pH4jX7ws
同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。886Please respect copyright.ＰＥＮＡＮＡVco0Eahs2m
886Please respect copyright.ＰＥＮＡＮＡ6ingOOxZzA
Link:886Please respect copyright.ＰＥＮＡＮＡEMHwHaxKqk
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio886Please respect copyright.ＰＥＮＡＮＡU1K8wnShCI
886Please respect copyright.ＰＥＮＡＮＡ2Rmk2JQqcs
有興趣接收科學資訊的話，歡迎follow IG: potatopigtongue。886Please respect copyright.ＰＥＮＡＮＡ4NG9kLwa3C
886Please respect copyright.ＰＥＮＡＮＡQdYNq9ALV5
https://www.instagram.com/potatopigtongue/886Please respect copyright.ＰＥＮＡＮＡzt2euExs7x
886Please respect copyright.ＰＥＮＡＮＡKRCzznBkkn
886Please respect copyright.ＰＥＮＡＮＡA0UsUekuCO
Ref1:https://www.nature.com/articles/s41591-020-1118-7886Please respect copyright.ＰＥＮＡＮＡMxuFkZHo4z
Penana
search
登入arrow_drop_down
註冊arrow_drop_down
