我們身體的各部份均是由細胞組成，眼睛晶片也自當然不例外。786Please respect copyright.ＰＥＮＡＮＡOPpnG3pasY
但細胞裡頭有著各式各樣的細胞器官，例如負責製造能源的粒線體(mitochondria)、收藏DNA的細胞核(nucleus)等，它們顯然並不是透明的。786Please respect copyright.ＰＥＮＡＮＡiJbY4HZ5od
786Please respect copyright.ＰＥＮＡＮＡ07RXd0rmd8
究竟身體有甚麼方法可以製造透明且能讓光線通過的眼鏡晶片呢?786Please respect copyright.ＰＥＮＡＮＡZwCj6sy9dF
786Please respect copyright.ＰＥＮＡＮＡM6V9i15x9m
786Please respect copyright.ＰＥＮＡＮＡ2Ikx37Prta
786Please respect copyright.ＰＥＮＡＮＡYjTP7r9LdE
(圖2)答案很簡單，就是把那些細胞器官通通摧毀。786Please respect copyright.ＰＥＮＡＮＡXCCiqPV3sj
786Please respect copyright.ＰＥＮＡＮＡiZBCaZpIjI
786Please respect copyright.ＰＥＮＡＮＡmFpAeX7qIv
從圖中可見，晶片的外圍有著表皮細胞(Epithelial cells)以及纖維細胞(Fibre cells)，唯獨是中間區域的細胞，它們的細胞器官均接近得消失得一乾二淨。786Please respect copyright.ＰＥＮＡＮＡgiWYGirnDB
786Please respect copyright.ＰＥＮＡＮＡ9iA6Sp2RQt
786Please respect copyright.ＰＥＮＡＮＡ2ymMs5xCwA
(圖3)有科學家利用班馬魚作動物模型，並將兩款細胞器官分別染成綠色及紅色。786Please respect copyright.ＰＥＮＡＮＡHxt8sr2wcw
786Please respect copyright.ＰＥＮＡＮＡu9jg1MSSsE
786Please respect copyright.ＰＥＮＡＮＡ8UQ2QBaNcM
從圖中可見，直至班馬魚受精後約59小時左右，綠色及紅色均分別清晰可見及有著其獨特的分佈，表示兩款細胞器官非常健在。786Please respect copyright.ＰＥＮＡＮＡHamJq6daEs
但在約60小時打後，紅色和綠色開始有著衰退的現象，亦即表示細胞器官開始逐漸被受摧毀。786Please respect copyright.ＰＥＮＡＮＡU7b7CJx1xC
786Please respect copyright.ＰＥＮＡＮＡLhLfDsEJt4
786Please respect copyright.ＰＥＮＡＮＡixeKvbmEBz
(圖4)找出眼睛晶片的細胞器官被受摧毀的時段後，研究人員便著手進行一系列的實驗，786Please respect copyright.ＰＥＮＡＮＡ7BHJfs2PXY
並發現名為plaat的蛋白質負責在細胞器官的外膜進行破壞，因而引發細胞器官摧毀的過程。786Please respect copyright.ＰＥＮＡＮＡVo9qrsjcTW
786Please respect copyright.ＰＥＮＡＮＡ3rwfQbOnGX
786Please respect copyright.ＰＥＮＡＮＡbDCMAEdwjS
圖中為班馬魚的眼睛晶片，可見因為缺乏plaat蛋白質的緣故，細胞器官沒能完整摧毀，其晶片亦變得相對上混濁及不透光，影像亦較為不清晰。786Please respect copyright.ＰＥＮＡＮＡjrHfANYNSF
786Please respect copyright.ＰＥＮＡＮＡureQxIwbM5
786Please respect copyright.ＰＥＮＡＮＡMl1t9dHlcW
(圖5)除班馬魚外，研究人員亦有利用老鼠進行實驗。786Please respect copyright.ＰＥＮＡＮＡHtehOS5v8o
786Please respect copyright.ＰＥＮＡＮＡGruXAaCmXT
786Please respect copyright.ＰＥＮＡＮＡVXdtH3fU3F
跟班馬魚一樣，缺乏plaat蛋白質的老鼠眼睛晶片變得混濁及不透光，並影響視線。786Please respect copyright.ＰＥＮＡＮＡO2PuX1wi85
786Please respect copyright.ＰＥＮＡＮＡ1SHrWMHv8O
786Please respect copyright.ＰＥＮＡＮＡoc5M0gfU0l
786Please respect copyright.ＰＥＮＡＮＡRcu5kpRVZN
786Please respect copyright.ＰＥＮＡＮＡBMk7NNqybB
786Please respect copyright.ＰＥＮＡＮＡlGaOa4MiKQ
如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。786Please respect copyright.ＰＥＮＡＮＡc7RWgFlMuS
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Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc786Please respect copyright.ＰＥＮＡＮＡlyYQFAG5wF
786Please respect copyright.ＰＥＮＡＮＡ2RgREtX6UT
同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。786Please respect copyright.ＰＥＮＡＮＡbGg7ow14kF
786Please respect copyright.ＰＥＮＡＮＡU7VJALdpAU
Link:786Please respect copyright.ＰＥＮＡＮＡdlNRkdlfpY
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio786Please respect copyright.ＰＥＮＡＮＡCRp8nXUZmh
786Please respect copyright.ＰＥＮＡＮＡHWzQeQwbEH
786Please respect copyright.ＰＥＮＡＮＡRhfW78PsQ0
除非Facebook及IG重開侵侵的account，否則我的IG將不會再作更新，只會寄居本土LIHKG及Penana。786Please respect copyright.ＰＥＮＡＮＡLgLKQzlSiC
786Please respect copyright.ＰＥＮＡＮＡ6cGO77ktUU
Ref1:https://www.nature.com/articles/s41586-021-03439-w786Please respect copyright.ＰＥＮＡＮＡMYKqAJ87fL
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